Burkitt's Lymphoma- A cancer of the lymphatic system, associated with the Epstein-Barr virus and also the cause of mononucleosis as well as other cancers. It is characterized by a large osteolytic lesion in the mandible or by a mass in the retroperitoneal area. It is a high-grade B-cell neoplasm and has 2 major forms, the endemic (African) form and the nonendemic (sporadic) form. Burkitt lymphoma is a childhood tumor but it is observed in adult patients. It is one of the fastest growing malignancies in humans, with a very high growth fraction.
Pathology- tangible body macrophages scattered throughout small round blue lymphocytic background yielding a "starry sky" pattern.
Pathology can be educational as well as pleasing to the more artistically attuned;
(See the macrophages cells with the abundant cytoplasm, giving them a halo appaearance, sprinkled amongst the b-cells lymphocytes? --Now take a look at Vincent Van Gogh's Starry Night!)
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